Question: BWA-MEM rather than bowtie2 in UKBB exome-sequencing alignment
0
gravatar for Shicheng Guo
5 weeks ago by
Shicheng Guo8.0k
Shicheng Guo8.0k wrote:

Hi All,

Who knows why UKBB applied BWA-MEM rather than bowtie2 for the first 50,000 UKBB exome-sequencing alignment?

Thanks.

exome-sequencing • 107 views
ADD COMMENTlink written 5 weeks ago by Shicheng Guo8.0k
1

Were they considering Bowtie2?

I don't know how UKBB chose their pipeline, but most exome sequencing projects (for example, TCGA or gnomAD) use BWA, so it's not a surprising choice.

ADD REPLYlink written 5 weeks ago by igor9.2k
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 2076 users visited in the last hour