How is the Bolt LMM INFO Score calculated?
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19 months ago

Hi

I am trying to find what exactly does the INFO score from the results of Bolt LMM measure (there is nothing in the user manual and google has come up empty). I am assuming that it refers to the imputation accuracy taken from the genotype probabilities but does anyone have a link or know what is the theory/formula that it is derived from?

Thanks heaps

BOLT LMM • 521 views
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If you have programming experience you could look at the code otherwise consider emailing the program author directly.

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19 months ago

Thanks genomax. I did as you suggested and contacted the developer. It is calculated using the formula developed by [Marchini and Howie] in their 2010 Nature Review Genetics paper.

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