Closed:Senior Scientist, Computational Biology at Bit Bio in Cambridge, UK
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4.3 years ago

Location: Cambridge Biomedical Campus

Type: Full time, permanent / Start: Immediate

Salary: Competitive / Hours: 40 p/w

Your role in our team:

To execute and lead our ambitious research programmes for uncovering core transcription factor programs that define human cell types, we are looking for highly motivated and skilled senior scientists to join our growing team. You will become a key player in the delivery of strategic research projects, involved in their design, the analysis of experimental data and subsequent planning of further scientific development. You will be supervising junior and assistant scientists work towards project completion. This is an opportunity to join one of the best stem cell reprogramming labs and conduct research with a real-world impact.

Your key responsibilities include:

  • Delivering multidisciplinary research programmes contributing to the design and analysis of data from experimental projects
  • Develop and maintain internal infrastructure, including the creation of well documented user-friendly tools
  • Working collaboratively with experimental and computational biologists and leading projects including supervision of junior and assistant scientists
  • Developing new research ideas with the scientific, business and leadership teams
  • Contributing to strategic collaborations with key opinion leaders
  • Providing technical and scientific expertise by contributing to proposals, meetings, publications and business development activities
  • Disseminating Bit Bio’s vision and research to external scientific and lay audiences

You:

  • will join Bit Bio as a keen team player driven by a passion for scientific discovery and cell biology.
  • enjoy tackling research challenges through critical thinking, scientific rigour and inventiveness.
  • are comfortable working to tight timelines and managing workload and priorities.

Your practical research experience and excellent organisational skills will allow you to work independently, provide leadership on project execution, be productive and output driven whilst building efficient and positive collaborations with the wider team.

With essential experience:

  • A minimum of 3 years of post-doctoral experience in an area relevant to computational biology (or equivalent experience), and at least 4 years of experience doing primarily computational biology, ideally in the genomics space (can include time in PhD)
  • Strong computational fundamentals including machine learning, algorithms, and data structures
  • Proficiency in R and/or python
  • Experience analyzing large datasets, including next-generation sequencing data, in high-performance computing environments
  • Strong biological knowledge and interest, and familiarity with major biological data resources

… and possibly

  • Experience in data analysis of programmed human pluripotent stem cells and/or products of mammalian cell genetic engineering (CRISPR, lentiviral vectors)
  • Knowledge of up-to-date molecular biology techniques, haematology and/or immunology
  • Experience with version control, and using AWS or other cloud computing platforms for bioinformatics
  • Familiarity with gene regulatory networks, mechanisms of gene expression, and developmental biology
  • Experience with RNA-seq (bulk and/or single cell), microarrays, ChIP-seq, ATAC-seq, and/or other genomic technologies
  • Experience in industry

You are welcome to apply

To be part of our dynamic, growing start-up team and share our vision to build together the leading cell coding company please send your CV and cover letter to careers@bit.bio

machine-learning ChIP-Seq R sequencing RNA-Seq • 190 views
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