Can you help me understand why the following variant has a fisher stand (FS) phred-scaled P value of 0?
11 65107949 . G A 48.06 PASS AC=1;AF=0.500;AN=2;DP=73;FS=0.000;MQ=245.31;MQRankSum=7.260;QD=0.66;ReadPosRankSum=4.771;SOR=0.633;FractionInformativeReads=1.000;R2_5P_bias=-4.567 GT:AD:AF:DP:F1R2:F2R1:GQ:PL:GP:PRI:SB:MB 0/1:42,31:0.425:73:25,19:17,12:47:83,0,50:4.806e+01,8.983e-05,5.300e+01:0.00,34.77,37.77:25,17,18,13:24,18,14,17
I know FS isn't calculated when, for example, there are no forward (or reverse) strands. Are there other situations when it's not calculated?
Please let me know if there's any additional information that would be helpful
Thanks very much