When using Eagle, is the X chromosome typically phased without including pseudoautosomal regions?
0
0
Entering edit mode
4.3 years ago
curious ▴ 750

Phasing human samples with Eagle 2.4.1.

I have PAR regions on chromosome 23 right now.

I know I can use PLINK 1.9 split-x to move them to chromosome 25, then submit chromosome 23 to Eagle to basically phase only the non-PAR regions.

From reading Eagle the documentation sec 4.1.1 (https://data.broadinstitute.org/alkesgroup/Eagle/), I get the impression that chromosome 23 is phased without PAR regions and that trying to phase PAR regions can be inaccurate. My question is: In general do people just phase 23 non-PAR regions with Eagle?

Thank you

eagle phasing • 1.1k views
ADD COMMENT

Login before adding your answer.

Traffic: 1889 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6