Hi! I have a list of mutations and I want to check how many of them are germline mutations and appear in the dbSNP. I download the VCF file from dbSNP, but this is a very heavy file and i can't find a way to upload it and compare it with my list. Do you have any ideas for a solution for what i need?
I tried to download and install bcftools but for some reason can't use it (get multiple errors) and I'm not even sure this is the right direction for me.
Thanks in advance!