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3.3 years ago

MMK
▴
20

Hello everyone, I have an undirected network and I used cytoscape to visually represent the network. I calculated the different network properties using NetworkAnalyzer and CentiScape.

The values of Betweenness differ and I suspect NetworkAnalyzer might do a normalisation step not done in CentiScape. For example:

Betweenness unDir (CentiScape) = 345.8214 BetweennessCentrality (NetworkAnalyzer) = 0.012

Does anybody has seen the same and knows why?

Cheers

I think what you suspect is indeed true. According to documentation of NetworkAnalyzer, they do normalize the value obtained by summing over all possible nodes in network by factor of

(N-1)(N-2)/2(source - https://med.bioinf.mpi-inf.mpg.de/netanalyzer/help/2.7/index.html#nodeBetween). However, CentiScape does not seem to normalize and use the "summed" value as betweenness centrality measure (source - http://www.cbmc.it/~scardonig/centiscape/CentiScaPefiles/CentralitiesTutorial.pdf)That's good enough to be an answer