Entering edit mode

4.4 years ago

kanwarjag
★
1.2k

I have results of expression as Fold change and Z score. The Z score is a negative value while FC is >1.2. I was wondering what should be used FC or Z score. I understand that z score is the deviation from mean value and can be plus or minus.

You are right I have large negative z score with positive FC. How do I calculate |Z| , I googled it but could not find. So what should be considered FC

|Z| refers to the absolute value of Z. What I mean is, in the absence of any p-values, explore the following as your cut-offs:

You did not answer my question about how the data was processed, so, I cannot help you further. It is interesting and surprising that you have been presented with data that has no p-values.

Also be weary of whether or not your 'FC' values are linear, natural log, or log [base 2] fold changes.

Good luck.

My apology- P values are there raw p values looks good <0.01 That is the reason I could not grasp what is happening and what to use. Again thanks

Cool