hi-c coverage for scaffolding

Question

[Picasa]

Hey all

What is the minimum and optimal coverage for Hi-C data in order to get the best results after scaffolding?

Is there a coverage cutoff?

Thanks for your help

[i.sudbery]

Dear Picasa, you should probably include details of the type of organism, or at least the genome size you are interested in, and the sequencing strategy you are using for the rest of the genome. You should probably also make it explicit that you are using this for de-novo assembly. rather than 3D genome structure determination.