Entering edit mode
4.2 years ago
dle
•
0
Dear all,
I recently found a gene highly regulated during a disease I am interested in.
I would like to find all correlated genes and group the significantly correlated genes in pathway using a known database such as REACTOME.
The idea is to link the dysregulated gene I found to other major pathways well documented to be regulated during the disease.
In my head, I would see my interesting gene in the center of a plot and all the correlated genes around, sorted by pathway.
Would anyone have an idea to perform this kind of analysis?
thank you very much David
Not sure if this would help : I tried doing something similar using Cytoscape, I had a "node" of interest and I was able to extract associated interactions of that node from various different datasets (so a network which is formed by extracting information associated with my "node" of interest from various other datasets). Maybe you could try something along those lines?