Meta analysis to find candidate genes
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4.2 years ago
au.rinki.bio ▴ 20

hi, I am working on the different subtypes of particular cancer and trying to find out candidate genes that are common in these subtypes. To achieve this objective I had considered different microarray gene expression datasets. 1. During the selection of dataset criteria, I have considered only the dataset which has all the subtypes in a single study, not others. is it the right way to consider the datasets? 2. Because I am trying to find out common candidate genes so that I consider the data irrespective of grade, stage, and mutation in different genes like in a dataset, 1 subtype has a mutation in P53 genes others have not. Should I follow this criterion? Thanking you

Microarray • 692 views
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