Hierarchical Clustering of Single-Cell Counts

Question

[bioinformatics2020]

I have a normalized cell-matrix of about 10,000 cells that I would like to run hierarchical clustering on. I've already done a graph-based clustering approach, and this is something as an added analysis.

I've been following this guide (CH 10) https://osca.bioconductor.org/clustering.html#hierarchical-clustering However, I was wondering if there were any better approaches.

[jared.andrews07]

Is there a particular purpose for the clustering? Why isn't the method specified sufficient?