Finding paralogs of MYC gene

Question

[osaamashehzad95]

How do I find paralogs of MYC gene?

Answer 1

[Mensur Dlakic]

This sounds like homework, and it probably isn't something this community should be solving for you. BLAST will get you going - try both nucleotide blast and blastx. Google has answers to other questions since they are fairly standard.

[osaamashehzad95]

Thanks @Mensur for giving a starting point.

I agree, I don't want the community to solve this for me. Simply guidance. I am specifically stuck at the Translation of the sequence in all possible frames AND identify (for each frame) which codons are actually used in the gene it belongs to

Can you please guide me more specifically for this one?

[Mensur Dlakic]

Pasting "Translation of the sequence in all possible frames" into Google will get you going. Look to the right side of this page for answers to similar question. If you have no idea what these terms mean, it would be difficult to give you guidance here without doing a constant back-and-forth which is not ideal for this medium. Again, these are topics that can be learned well from Google if you invest some time. Here is another link to a Google search seeded with "gene exons introns codons paralogs". Making similar inquiries will get you plenty of answers in no time.

[osaamashehzad95]

Thanks @Mensur! I do understand what introns, exons, codons, and translation in all six frames mean. I just did not know the tool. Now I know that for any sequence, we can use NCBI's ORF Finder. But I have another question.

I know that my sequence is from MYC gene. But, how do I find its paralogs in NCBI?

[osaamashehzad95]

Thanks @Mensur for giving a starting point.

I agree, I don't want the community to solve this for me. Simply guidance. I am specifically stuck at the Translation of the sequence in all possible frames AND identify (for each frame) which codons are actually used in the gene it belongs to

Can you please guide me more specifically for this one?