Question: (Cytoscape) What app is for mRNA-chemical interaction?
0
gravatar for hslee97
8 months ago by
hslee970
hslee970 wrote:

I have used STITCH app for analyzing the mRNA-chemical compound interaction. But, STITCH app is for protein, not mRNA. In this case, Am i use STITCH app okay?

cytoscape • 216 views
ADD COMMENTlink modified 7 months ago by scooter380 • written 8 months ago by hslee970
2
gravatar for scooter
7 months ago by
scooter380
scooter380 wrote:

Hi,

Probably not, but maybe. It really depends on the scores. STITCH is giving you functional associations (not strictly physical interactions), as such, many of those edges might be valid. For example, an article describing an interaction between a compound and the mRNA for a protein would probably be picked up by the text mining algorithms. On the other hand, if the evidence is based on physical interaction, then you are probably getting binding events between the compound and the protein.

-- scooter

ADD COMMENTlink modified 7 months ago • written 7 months ago by scooter380
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