Variant calling from short/long read hybrid BAM
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12 months ago
Vitis ★ 2.4k

Is there an approach that takes in a hybrid BAM that contains both short and long reads and call variants, especially bigger structural variants? I think it will be more common to have both long and short reads for a genomic region. A variant caller that takes advantage of the hybrid data may be valuable, just as hybrid genome assemblers.

SNP sequencing • 269 views
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