I was trying to replicate a work present here wherein they have mentioned
We extracted DNA sequences for regions of 1001 bp centered at the enhancer midpoints (columns 7–8 of the BED12 file) using the BEDTools
However, in UCSC BED12 format description, the 7th and 8th columns represent the thick start and thick end. Shouldn't the average of the end and start coordinate considered as the center of the enhancers. Please help me understand this.
chr1 956563 956812 chr1:956563-956812 0.01 . 956664 956665 0,0,0 2 57,102 0,147
for this enhancer line from the BED12 enhancer file from FANTOM5, how can 956664 be center to enhancer when the center of enhancer should be ((956812-956563)/2)+956563 i.e. 956687.5 or 956687 and 956688 as a range.