Methylation analysis if no normal control
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2.3 years ago
9521ljh ▴ 50

I have methylation data, beta value of cancer patient. but only tumor sample i have, no control. There is no normal control in TCGA portal data for reference.

And i also have RNA expression value.

i want to find cancer driver gene of these samples.....but i'm stuck in now.. There's no any paper analyze methylation only tumor sample.

i am gonna search genes which have negative correlation between RNA and methylation value.

is there anything i can do for analysis more?

rna-seq • 447 views
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is there anything i can do for analysis more?

No, not really. You don't have enough data to perform any meaningful analysis.

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