Query regarding the cutoff values for the level 5 data of connectivity map
Entering edit mode
19 months ago
iti.gupta ▴ 10

Hello Everyone, For one of my analysis, I have used the connectivity map level 5 data. I am aware that these are moderated Z-scores (https://www.cell.com/action/showPdf?pii=S0092-8674%2817%2931309-0). However, my analysis requires a filtering step in which I have to filter the upregulated and downregulated genes upon the drug/compound treatment. Could anyone please help me with the best suitable cutoff values that could be used? (Or rather how should I infer the values of level 5?) Looking forward to hearing from you all.

Connectivitymap • 278 views

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