Question: Comparing variants in family trios in Python
0
gravatar for MediumHeat
11 weeks ago by
MediumHeat0
MediumHeat0 wrote:

Hello guys! Im pretty new into Bioinformatics and have some questions about it. Im currently working with a VCF-File with more than 1 Person in it (Mother,Father,Child) in Python. My problem right now is that i have the allels from everyone in the file but when you are looking at the childs allels i need to tell the user which allel comes from the mother and which from the father or none. I would be very thankful if someone could give me some hints to do this in Python and help me finishing the task.

I thank you in advance for your help

Stay safe!

snp • 145 views
ADD COMMENTlink modified 6 days ago by mikpom0 • written 11 weeks ago by MediumHeat0
2
gravatar for brunobsouzaa
11 weeks ago by
brunobsouzaa180
Brazil
brunobsouzaa180 wrote:

Don´t know in Python but you can use vcf-isec for this task. It´s pretty easy to use and you can intersect the child´s vcf with each parent and get the output for each intersection!

Hope it helps.

ADD COMMENTlink written 11 weeks ago by brunobsouzaa180
0
gravatar for mikpom
6 days ago by
mikpom0
Novosibirsk
mikpom0 wrote:

I was recently developing a Python package genomvar to work with genomic variants in Python data analysis ecosystem.

It is rather new but maybe you find it of use.

ADD COMMENTlink written 6 days ago by mikpom0
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