How test for overlap in gene ontology categories, between two gene lists?
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18 months ago
crespi ▴ 10

I have two lists of genes (Gwas hits for 2 diseases). I want to see if the two lists show more overlap in GO terms (eg KEGG pathways, Biological Processes) than expected by chance. How might I go this? I am concerned about the hierarchical structure of the GO terms.

Gene ontology • 468 views
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