Question: How To Build Gene Network Biology ?
1
gravatar for madkitty
8.6 years ago by
madkitty620
Canada
madkitty620 wrote:

I've seen wonderful gene networks recently published. Is there any way to do this from a list of gene ? What do I need ?

gene network biology • 2.0k views
ADD COMMENTlink modified 6.8 years ago by Biostar ♦♦ 20 • written 8.6 years ago by madkitty620
2

From a list of genes? No. From a list of genes with some kind of data that indicates the interactions between them? Yes.

ADD REPLYlink written 8.6 years ago by Neilfws49k
1

can you give us some example what you saw?

ADD REPLYlink written 8.6 years ago by Gjain5.5k
1
gravatar for ff.cc.cc
8.6 years ago by
ff.cc.cc1.3k
European Union
ff.cc.cc1.3k wrote:

As said Neilfws you need pairwise information, e.g.

-a tab separeted text file like this

gene1   interaction gene2
ABC1    2   BRCA2
ABC1    2   BRCA1
BRCA2   2   XRCC1

-a tool for graph visualization (e.g. cytoscape, graphviz...). In cytoscape you should import a new network from table/csv and setup source (gene1), destination (gene2) and interaction type (interaction) column from the wizard.

-look at the graph

p.s. I suggest at least reading the good cytoscape tutorial

ADD COMMENTlink modified 8.6 years ago • written 8.6 years ago by ff.cc.cc1.3k
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