Question: gene expression correlation positive controls scRNAseq
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guillaume.rbt • 830 wrote:
Hi all,
I'm currently testing tools to assess the correlation of gene expression with scRNAseq human data.
I would like to have housekeeping "positive controls" of two genes that are always highly correlated, in any type of cell.
Would anyone know an example of a pair of gene like this?
Thanks
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modified 8 months ago
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geek_y ♦ 11k
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8 months ago by
guillaume.rbt • 830
One potential resource: https://www.tau.ac.il/~elieis/HKG/
Of course, with the dropouts in scRNA-seq, it's going to be difficult to get any meaningful correlations.
thanks ! I've found ABCF1 and ABCF2 that seems to be good candidates (R=0.81 on all TCGA normal samples)
TCGA is not single-cell. Did you mean "RNAseq" instead of "scRNAseq" in the title?
I used TCGA to check quickly the correlation between the genes, but I indeed work on scRNAseq.