Relatedness check for trio samples (Proband/Parents)
0
0
Entering edit mode
17 months ago

How can i check the relatedness for trio (parents/proband) WGS/WES clinical samples? Currently i use the overlapped variants approach for that. But are there any other reliable methods that can work for the trio samples. I've tried "vcftools --relatedness2" but that didn't work for me.

next-gen relatedness vcftools vcf SNP • 587 views
ADD COMMENT
1
Entering edit mode

Have you seen somalier?

ADD REPLY
0
Entering edit mode

No, i haven't. Thank you for the suggestion.

ADD REPLY
0
Entering edit mode

You could use plink or KING.

ADD REPLY
0
Entering edit mode

Can't use these two as both need a PLINK style PED files, and our online portal processing doesn't support that format. Thank you!

ADD REPLY

Login before adding your answer.

Traffic: 2895 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6