I am trying to analyze an "Illumina HumanHT-12 WG-DASL V4.0 R2 expression" beadchip.
However, when I open the non normalized data series, several negative values are present.
Most of them are very large(for example, -20)
Please guide me how should I deal with these negative values.
Is it correct to change all negative values to 0?
I am looking forward to your comments