Does anyone know how to use seurat to analyze MNN normalized single-cell sequencing data? The data I want to re-analyzed compromise several subjects, and it was combined and batch normalized using MNNs (the author used mnnpy to remove the batch effect). They only provided the batch normalized data without the raw count matrix data, so I'm curious whether this batch normalized data can be proceeded by seurat. Because seurat uses the raw matrix data as input data and it uses CCA to remove the batch effect. If yes, could you tell me which seurat tutorial should I use?
Question: Can I use seurat to analyze the data after MNNs batch normalized?
8 months ago by
jiandan123 • 0
jiandan123 • 0 wrote:
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