Weighted gene regulatory networks
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17 months ago
hkarakurt ▴ 130

Hello everyone, I need a transcription-factor gene network that has edge weights (or scores). I have networks from several databases but as I see regulatory networks are unweighted mostly.

Does anyone knows a weighted data set or any way to create weights?

Thank you in advance

regulatory ChIP-Seq network • 358 views
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Entering edit mode
17 months ago

There are many possible answers to your question. You can technically 'weight' a graph by any metric that you want. However, if you are starting with an unweighted network, then it would be difficult to weight it by, e.g., correlation coefficient, due to the fact that that information would be already lost.

My only recommendation is for you to continue searching for datasets online, and / or try to obtain the original data for the networks that you have already accumulated (by having the original data, you could then re-create the networks, but having their weights included this time).

Kevin

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