I'm working on some downstream analysis of some single cell samples, and I'm trying to decide which clusters are worth investigating further to see if they contain subtypes. Is there a method similar to Intra-class Correlation Coefficient from sample design theory that I could use to determine which clusters are more / less internally homogeneous? I've though about using variance of highly expressed genes, but I think that's a bit too clunky of a metric.
Question: Estimating hetero/homogeneity of scRNAseq clusters
6 months ago by
jrleary • 170
Lineberger Comprehensive Cancer Center
jrleary • 170 wrote:
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