How to get nucleotide sequence of the foxp3 enhancer ?
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4.4 years ago
zhuobaowen ▴ 40

Hello everyone, I am doing some research on the regulation of FOXP3 expression, FOXP3 has three enhancers, also known as CNS1, CNS2, CNS3, but I want to get the nucleotide sequence of the FOXP3 enhancer and its location. Does anyone know how to search it and get it? Thank you so much!

ChIP-Seq RNA-Seq • 1.0k views
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Hi,

Did you check the NCBI database?

António

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yes, I only get the sequence of transcrips of FOXP3 from NCBI GENE database, but I don't know the location of CNS.

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For mouse genome the sequences seem to given in the supplement of the paper here (page 20 of the supplement of the paper doi: 10.1038/nature08750 . You can blat the sequences on to mouse genome in the UCSC genome browser to get the genomic location.

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OK,thank you so much

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