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11 months ago
MatthewP ▴ 990

Hello, I have omics data for a few patients(assume < 20 cases). I would like to learn how others analysis omics data of cancer patient, but I can't find some paper use such few samples(Maybe because the heterogeneity of clinical sample requires large sample scale).
How do I search paper do omics analyse on any cancer sample(no cell line data) with few cases?

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What kind of omics data and what kind of analysis are you trying to do? There are many papers with varying sample sizes, even as low as a single patient. It really depends on what you are trying to do.

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Multiple omics(WGS, WGBS, RNA-seq...) data will be released. I didn't decide what kind of analysis yet because it's very early stage, I am reading papers(biology and bioinformatics) try to work out some plans currently.

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This sounds like a relatively big project. You may want to consult with whoever is organizing it to help you with getting started. There is probably already some sort of a grant that has a lot of background and related publications.

If you just search for something like "disease_name genomics" or "disease_name wgbs", you'll probably get some reviews with many relevant citations.

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