Calculating HRD score
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3.7 years ago
vctrm67 ▴ 50

Has anyone successfully calculated the HRD score (using nTAI, LOH, and LST)? I tried using the script provided in this paper (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443545/) but it does not seem to work. Specifically, there is a function "check.names" that references an 11th column of a matrix that isn't required by the program (which requires a 10 column matrix).

HRD • 2.2k views
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Do you need to use that script specifically? If you just want to calculate HRD scores, there is also scarHRD, which worked well in my experience: https://github.com/sztup/scarHRD

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Please share the link to code or host the code some where else and share the link (if that is okay with authors). Please also provide input file example.

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Has anyone an update about the script provided in the paper. I am getting the same error. Has anyone figured out a solution? Thank you in advance!

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