Hey all, I have been trying to model my sequences via swiss-model and I believe if im not mistaken a good/ok model is determined by a higher QMEAN>-4.0. I am wondering how a structure can get such a low QMEAN i.e. -7.0 if the sequence identity between the template and target are 100%? For example I am taking an e.coli sequence and modeling it on a e.coli structure and the QMEAN is terrible? Am I going about this the wrong way? I am trying to get as good of a model as possible, are there other statistics to consider? The GMQE explained by swiss-model is not very intuitive but I guess it is used to rank models in your search.
Thanks