Closed:How to perform enrichment (overrepresentation) using custom path sets in R

Question

[SupBioInformatics]

Hi,

I am trying to do enrichment analysis (specifically using ORA) for metabolites with own path sets. For example, I have compounds expression data with compound names/HMBI/KeggID, and I have a custom compound set, which have 200+pathways with corresponding compounds. I would like to do ORA enrichment on the compound expression data using my own custom compound set.

I know clusterprofiler has enricher function andI tried it, but it seemed only work for genes. Is there any other packages or function I can do enrichment using own pathways set? My goal is to see what pathways I can map using ORA.

Thank you in advance.