**400**wrote:

Hi everyone. I'm studying two SNPs in a case/control study and one part of the analysis is to test for additive model. So the question is: Can I use logistic regression for this task or should I just build a 2x2 table and perform Fisher exact test? The data looks like this:

```
Outcome SNP_1 SNP_2 Gender Age
1 AA GG M 45
0 AC GT F 54
1 CC TT F 65
```

Outcome = 0 (Control); 1 (Case)

SNP_1: A = Risk

SNP_2: T = Risk

For logistic Regression, how can I format my data to fit in this kind of model? Should I just convert my genotypes to 0, 1, 2, merge both SNPs into a single column and use `Outcome ~ SNP, family = binomial`

or there's another way to do this?

Thanks.