Which is correct when considering minor allele freq (MAF) for a given gene?
1) Add all MAFs together and square result. Multiply times population to get total number of homozygous recessive individuals in a population; or 2) Square each MAF and multiply by population to get homozygous individuals. Add all homozygous individuals to get total number of homozygous recessive individuals?
Please let me know if I need to clarify anything.
Thanks so much!