How to do a network analysis using Post-GWAS data?
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3.5 years ago

Hello, I have 50 traits and I performed GWAS on each of them. Unfortunately, I have obtained significant SNPs above a false discovery rate (5%) for only 9 traits. Using Bedtools, I could extract the distance of all the SNPs from different genes for different traits. Is it possible to do a Network analysis with this kind of data? Can you please give some links to the tutorial for network analysis?

As I have the effect of each SNP from all the 50 traits (irrespective of significance), is it also possible to do a network analysis using all the SNP effects for 50 traits?

I have never done a network analysis and do not have any idea. It is because a reviewer just asked me to do this analysis. And I am really struggling to get an idea of how to do that.

Any feedback is highly appreciated. Thank you.

SNP gene R genome • 749 views
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