Entering edit mode
3.4 years ago
tb_2020
•
0
I have BAM files (human; whole exome) that I would like to visualize on IGV to see if there is any evidence of loss of heterozygosity (LOH). My impression is that you can potentially see evidence of LOH in case of a classic point hit (Kundson) and/or copy-neutral LOH. For more complex LOH, such as those arising after mitotic disjunction, I would say it won't be possible to determine by simply looking at raw reads. Does everyone agree with my assessment?
Or does anyone know if there any good ways of detecting LOH accurately on IGV (or any other publicly available viewers?)