Tool: Pintron: Gene-Structure Prediction Based On Spliced Alignments Of Transcript Sequences
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6.9 years ago by
gianluca.dellavedova50 wrote:

PIntron is a tool for computing the exon/intron structure and the full-length isoforms of a genomic regions from a set of transcripts and the genomic sequence.

It computes the splicing alignments of the transcripts against the reference genome, it amalgamates the alignments to compute the exon-intron structure and then it computes the full-length isoforms.

PIntron is a command-line set of program that can be run on Linux 32/64 bit or Mac OS X. It is released under the open source AGPLv3 license.

The program (source code) and documentation can be found at To compile PIntron you need the usual GNU toolchain. To run it, you need Python and Perl.

Below is the the full-length isoforms computed on gene TP53. The set of full-length isoforms for the gene TP53

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