I am trying to merge ~ 10,000 of vcf files into one vcf file, and I run to
bcftools merge but it failed (segmentation fault) due to the large number of vcf files which I guess it is a software limitation. Then I tried to do so as batchs of 2000 vcf files at a time, which just worked fine, results in five sets of multi-vcf files (2000 samples each).
The question is how can I combine these multi-vcf files into one large multi-vcf file?
Any advice and suggestions will be greatly appreciated.
Thanks for your quick reply. It actually works!
You're welcome. Please click on the green check mark to accept my answer and mark your question as resolved.