My tutor let me find some papers about alternative splicing to study myself.
And I find this process is more common in cancer study not in plant study.
Is this phenomenon true?
If it is true, why?
Yes, the alternative splicing (AS) rate is very higher in humans (~95%) as compared to plants (~60%). The seemingly lower number of genes undergoing AS in plants when compared to humans (~95%) could be due to lack of enough studies or in-depth annotations of the plant genomes. In early reports dating back to 2004, the AS rates in the model plant Arabidopsis was reported at a meager ~11.6%, when the AS rates in humans was ~42%. Efforts by several groups over the years, and with the advent of high-throughput sequencing technologies, the AS rates in Arabidopsis and humans ascended comparably to ~60 and ~95%, respectively.
References: https://www.frontiersin.org/articles/10.3389/fpls.2019.00740/full https://www.sciencedirect.com/science/article/abs/pii/S136952661500028X https://pubmed.ncbi.nlm.nih.gov/19858364/ http://www.plantcell.org/content/27/1/71
might be some truth in that indeed.
splicing defects are long time studied in the field of cancer research, since they are know to be quite important there.
In plants, alternative splicing has long be somewhat neglected, both due the fact that the input data was less than in human/cancer research and on the other hand alternative splicing is less of a topic in plants but it's catching up recently. One other theory is that alternative splicing is less prevalent in plants because they rely on other mechanisms (eg. gene duplication, which is much more present in plants than other species and it is hypothesised plants rather duplicate genes to get to 'new' forms rather than using AS like in human )
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Thanks for your answer, it helps me a lot.