PLINK beta coefficient
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14 months ago
seta ★ 1.5k

Dear all,

I analyze the genetic variation association with a given quantitative trait using PLINK. As I found, this tool reported a beta coefficient per one minor risk allele; so, this value (beta) will be multiplied in 2 for the individuals with two minor risk alleles, yes? However, the beta value of two risk alleles can not be exactly two-fold of one risk allele even under the additive model, isn't it?

Any comments would be highly appreciated

GWAS association beta coefficient PLINK • 603 views
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