One Ph.D. position in Bioinformatics is available at the Department of Biomedical Sciences, Chosun University for the 2021 spring/fall session.
The Ph.D. position is fully funded through professor funding from various projects under the Korea Government.
Kinases and G-protein coupled receptors (GPCRs) play various important roles in cellular signallings and biological functions. Hence, their aberrant activities are associated with various cancer types, autoinflammatory diseases, and neurodegenerative diseases, making them a hot target for drug design. Consequently, the development of inhibitors that target these proteins constitutes a major research interest. Computer-aided drug design techniques have emerged as effective tools in the arena of drug design. Taking advantage of the computational tools, the student will perform research in the area of structure-based drug design using available state-of-the-art techniques. Molecular docking and molecular dynamics simulation will be used to study ligand-protein and protein-protein interactions in the context of protein kinases and G-protein coupled receptors (GPCRs). 3D-QSAR techniques will be used to study structure-activity relationships.
Recent Papers from the group:
- Keretsu, S., Bhujbal, S.P. & Cho, S.J. Rational approach toward COVID-19 main protease inhibitors via molecular docking, molecular dynamics simulation and free energy calculation. Sci Rep 10, 17716 (2020). https://doi.org/10.1038/s41598-020-74468-0
- Keretsu, S.; Ghosh, S.; Cho, S.J. Molecular Modeling Study of c-KIT/PDGFRα Dual Inhibitors for the Treatment of Gastrointestinal Stromal Tumors. Int. J. Mol. Sci. 2020, 21, 8232. https://www.mdpi.com/1422-0067/21/21/8232#cite
- Keretsu, S., Bhujbal, S.P. & Joo Cho, S. Computational study of paroxetine-like inhibitors reveals new molecular insight to inhibit GRK2 with selectivity over ROCK1. Sci Rep 9, 13053 (2019). https://doi.org/10.1038/s41598-019-48949-w
Submission deadline: Applications will be accepted until the position is filled.
- A graduate/master's degree in bioinformatics, biophysics, biotechnology, pharmaceutical sciences, computational biology, or related fields with good computational skills. In addition, computer science students with an interest in biology may also apply.
- Proof of English proficiency certificates such as IELTS or TOEFL.
- Previous research experiences or awards/medals for academic excellence.
- Fully paid tuition fees by supervisor
- Competitive monthly stipend and incentives
- Seasonal tours organized by university
To apply, kindly sent a cover letter/motivation letter along with curriculum vitae in a single PDF file to Seke Keretsu (firstname.lastname@example.org). The letter may be utilized to address why the prospective candidate is suitable for the position. Selected candidates will be invited for virtual interviews.