Can RNA-Seq be used for TMB calculation?
1
0
Entering edit mode
5 months ago
rotemkat ▴ 10

Hi, I have RNA-seq data of cancer patients and their matched normal as well. I'd like to calculate for each patient the TMB, but I mostly find information about such calculations for Whole Genome/Whole Exome. Can you advice me what would be the best way to do such calculations? Thanks

RNA-Seq tmb • 210 views
ADD COMMENT
0
Entering edit mode
5 months ago

You could first call variants using the RNA-seq reads, but this is not ideal - see here: A: Inferring genotype based on RNA sequnces

Kevin

ADD COMMENT

Login before adding your answer.

Traffic: 1032 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6