Which tool for clustering (sub-networking) of protein-protein interaction networks based on the Gene Ontology Biological Process of proteins?
1
0
Entering edit mode
7 months ago
Farah ▴ 70

Hello,

I have a network of 100 proteins (without any quantitative or expression data) which I want to do clustering based on their Gene Ontology biological process inside the network to create some subnetworks of my initial network. In such a way that nodes to be coloured based on their cluster, and each cluster has its own colour. Also, after clustering, I need the layout of the initial network to be kept as before (not merging the nodes in a bigger node), and just each node to be coloured based on their cluster that they belong to. Also, shows the enriched Gene Ontology biological process of each coloured cluster. I was wondering if you could suggest me any tools especially from Cytoscape plugins that can create subnetworks using clustering based on biological process (similar to the attached figure, A part).

Thanks a lot for your help and advise.

Best regards, Farah

enter image description here

cytoscape clustering Gene Ontology sub-network • 686 views
ADD COMMENT
1
Entering edit mode
7 months ago
scooter ▴ 450

Answered on the Cytoscape helpdesk: https://groups.google.com/g/cytoscape-helpdesk/c/qFE4nf4o_xU

ADD COMMENT

Login before adding your answer.

Traffic: 1040 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6