Duplicated row names on Seurat
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4 months ago
fouerghi20 ▴ 30

Can you run CCLE data through the Seurat R package? My counts matrix has duplicated feature names, so I can't provide it as an input matrix to CreateSeuratObject() because it only takes matrices with non-duplicated row names (AKA feature names).

CCLE Seurat scRNAseq single cell • 350 views
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Why does it have duplicated feature names?

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I found an explanation basically saying that there are gene names that get duplicated because "there isn't consensus over which coding sequence represents the common name." I made the gene names unique and was able to create the Seurat object while preserving the structure of the matrix.

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