I have run strelka tool for variant calling on some data (bam files) and it has worked. However, when I wanted to run it again (after one month) on a larger cohort (the same data with other data) I got as output empty VCFs: There is a VCF header but no calls. There is no error in the logs files so I can't find where is the problem.
I have uninstall and install Strelka tool and run it again but I git always the same results: empty VCFs with only header and no errors in the logs file.
is there a reason for this? Thank you for ur help.