Survival analysis using differential gene expression

Question

[lopes-santosg]

Hello guys,

I need of a little help, please!

I have 343 patients with head and neck cancer, removed of TCGA. We find 898 differential gene expression (DEGs) between groups low and high expression.

We would like to assess the survival of our patients, with high and low expression, with some of our genes. Could you help me with this process? Please!

My DEGs are with the expression values. Should I separate them into high and low as well? What is the best way?

In summary: I would like to assess the impact on my patients' prognosis when the X pathway is with high or low expression, and also show the expression of Y DEGs.

Thanks

Answer 1

[ATpoint]

Survival analysis with gene expression