Difference between dbSNP vcfs
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4 months ago
whb ▴ 20

What are the differences between the dbSNP vcf from NCBI/EBI and Sanger? They are both based on GRCm38 but the file size are very different 1GB vs 5GB. So I wondered if they have different use? and how do I decide which one to use?

Sanger Mouse project: https://www.sanger.ac.uk/sanger/Mouse_SnpViewer/rel-1505

EBI: ftp://ftp.ebi.ac.uk/pub/databases/eva/rs_releases/release_2/byassembly/GCA_000001635.6_release2

Thank you!

dbSNP SNP vcf • 146 views
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4 months ago
yoh1242 ▴ 10

Their will always be difference in the different versions of dbSNP as they are updated. Use the latest version of dbSNP available on NCBI/EBI as they keep it updated.

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