RMA normalization for integration of RNA-Seq and microarray expression data?

Question

[jariani.abbas]

Hi,

I have collected a few hundred expression datasets from the same tissue type, from different platforms. Now I am trying to integrate them. My first thought for normalizing them in a manner that they could be compared, was using z-scores, but I wonder can RMA be used here? Or maybe first RMA for microarray data, and then z-scores?

[ATpoint]

May I ask why you do that and what the final analysis goal is? Please add some details.