Just beginning to work with exome sequence and I have a basic question. In my excel file there is a column labeled "gnomad filter." Within the column are the following notations: PASS, RF, AC0, INBREEDING COEFF, or blank. Trying to eliminate those results that are the result of poor qc. If these are listed, does that mean they passed or failed? What is the significance of each? Is better or worse than the others? My first run, I looked at only "PASS" but was so restrictive that it eliminated a mutation that we knew was there.