Question: The distribution F(S) of top-hit scores for a database search algorithm based on local sequence alignments follows an extreme value distribution F(S) = le^(−l(S−u)) exp(−e^(−l(S−u)) ) with l = 0.69 and u = 22. A couple of years later, the database has doubled in size. The distribution of top-hit scores should now be given by an extreme value distribution with
A: l = 0.81 and u = 22.
B: l = 1.38 and u = 24.
C: l = 0.69 and u = 44.
D: l = 0.69 and u = 23.
Right now I am completely new to bioinformatics. Can someone please provide me the correct solution with (if possible) explanation? The question's image is also linked at https://ibb.co/pQZNLmz Thank you in advance. NOTE: This is not a homework question or something like that. I've graduated and trying to study bioinformatics by myself.
